Community-acquired pneumonia
Cardiogenic shock
Brief resolved unexplained event (BRUE)
Bronchiolitis
Bronchiolitis is an extremely common lower respiratory tract infection in infants and young children. Symptoms can include fever, coughing, and signs of lower respiratory tract obstruction such as tachypnea, nasal flaring, belly breathing, retractions, head bobbing, and in young infants, apneas. Epidemiology Bronchiolitis is the most frequent cause of hospitalization for respiratory illness in infants […]
Anaphylactic shock
Anaphylactic shock is a severe, life-threatening allergic reaction that can occur rapidly and requires immediate medical intervention. This article provides an overview of the epidemiology, etiology, pathogenesis, pathophysiology, clinical features, diagnosis, and treatment of anaphylactic shock in children, tailored for pediatric residents. Epidemiology Anaphylaxis is a relatively rare but serious condition in children, with an […]
Acute asthma
Pathophysiology Asthma involves the triad of: Airway edema/inflammation that leads to mucosal swelling. Excess mucus production and subsequent mucous plugging. Bronchospasm/bronchoconstriction that leads to: Increased airways resistance: Causes increased work of breathing. Atelectasis and ventilation: Perfusion (V:Q). Mismatch: Causes hypoxemia. Image credit: Encyclopedia Britannica. Symptoms Occur after trigger exposure and resolve with trigger avoidance or […]
Bioterrorism and other zoonoses
Learning goals Describe the typical clinical presentations of anthrax, tularemia, botulism, plague, and smallpox Describe what makes a microbial agent a good candidate for a bioterrorism weapon and list clues that a bioterrorism incident has occurred in your community Identify the most common zoonotic exposures linked to infections with Bacillus anthracis, Francicella tularensis, Yersinia pestis, […]
Infectious arthritis
Optional resources Core EM Podcasts: Septic arthritis Estimated time: 20 min. This podcast reviews the essentials of septic arthritis, an orthopedic emergency that requires rapid recognition and treatment to prevent irreversible joint damage and systemic complications. It explains how bacteria reach the joint—most commonly through hematogenous spread—and how the resulting inflammatory cascade can destroy cartilage […]
Fungal infections
Learning goals Describe the basic structural features of yeasts, molds, and dimorphic fungi and the pathogenesis of fungal infections Compare and contrast the diagnostic methods for various opportunistic fungi, including serologic, histologic, and culture methods Describe the morphology and mycology of Candida and compare and contrast the anatomic sites, clinical manifestations, and approach to management […]
Antibiotics: Ribosomal/protein synthesis
Learning goals Compare and contrast the mechanism of action, spectrum of activity, and mechanisms of resistance of the various antibiotics that effect protein synthesis List common clinical uses and key adverse effects of the tetracyclines, macrolides, lincosamide (clindamycin), and oxazolidinones (linezolid) List common clinical uses, and describe the monitoring and key adverse effects of the […]