Rickettsia and arthropod-borne viruses
Learning goals Compare and contrast the epidemiology, clinical manifestations, pathogenesis, diagnosis, and treatment of the tick-borne diseases: Rickettsia, Anaplasma, and Ehrlichiosis Compare and contrast the key epidemiologic factors, clinical manifestations, complications, and prevention of dengue fever, chikungunya virus, Zika virus, yellow fever, and arbo-encephalitides Define “vector-borne disease” and “zoonotic disease” and identify strategies to prevent […]
Bioterrorism and other zoonoses
Learning goals Describe the typical clinical presentations of anthrax, tularemia, botulism, plague, and smallpox Describe what makes a microbial agent a good candidate for a bioterrorism weapon and list clues that a bioterrorism incident has occurred in your community Identify the most common zoonotic exposures linked to infections with Bacillus anthracis, Francicella tularensis, Yersinia pestis, […]
Fungal infections
Learning goals Describe the basic structural features of yeasts, molds, and dimorphic fungi and the pathogenesis of fungal infections Compare and contrast the diagnostic methods for various opportunistic fungi, including serologic, histologic, and culture methods Describe the morphology and mycology of Candida and compare and contrast the anatomic sites, clinical manifestations, and approach to management […]
Antibiotics: Ribosomal/protein synthesis
Learning goals Compare and contrast the mechanism of action, spectrum of activity, and mechanisms of resistance of the various antibiotics that effect protein synthesis List common clinical uses and key adverse effects of the tetracyclines, macrolides, lincosamide (clindamycin), and oxazolidinones (linezolid) List common clinical uses, and describe the monitoring and key adverse effects of the […]
Tuberculosis
Learning goals Described the unique microbiologic features of mycobacteria their role in infection and pathogenesis and the immunologic response Describe the epidemiology and clinical spectrums associated with the non-tuberculosis mycobacteria, M. avium complex and M. leprae Describe the epidemiology, pathophysiology, natural history, and clinical manifestations of Mycobacterium tuberculosis infections Compare and contrast the pros and […]
Pneumonia
Learning goals Define pneumonia and describe the pathogenesis of lower respiratory infections Compare and contrast the common bacterial causes of pneumonia in the following contexts: community-acquired, health-care-associated, persons with obstructive lung disease, immunocompromise, and aspiration Compare and contrast the clinical and diagnostic findings of typical and atypical community-acquired pneumonia Describe the clinical factors that are […]
Viral lower respiratory infections
Learning goals Describe influenza virus structures, virulence factors, and epidemiology and correlate to concepts of antigenic drift and antigenic shift Compare and contrast the virology, epidemiology, pathogenesis, clinical manifestations, complications, diagnosis, treatment, and prevention of influenza, severe acute respiratory syndrome coronavirus (SARS-CoV), and respiratory syncytial virus (RSV) Describe the common diagnostic methods for respiratory viral […]
Bacterial upper respiratory infections
Learning goals Compare and contrast the epidemiology, clinical features, complications, and approach to management of viral and bacterial causes of pharyngitis Describe the clinical manifestations, microbiologic features, diagnostic approach, and treatment of pharyngitis caused by Streptococcus pyogenes Describe the microbiology, epidemiology, clinical presentation, and approach to management of epiglottitis Describe the microbiology, epidemiology, clinical presentation, […]
Viral upper respiratory infections
Learning goals Compare and contrast the microbiology, epidemiology, and range of clinical syndromes associated with rhinovirus, adenovirus, seasonal coronavirus, and parainfluenza Differentiate acute viral respiratory illness from secondary bacterial infections and describe indications to use antibiotics for upper respiratory infections Describe the pathogenesis, microbiologic etiologies, clinical manifestations, diagnosis, and pharmacologic management of otitis media, otitis […]
Infections in the immunocompromised host
Learning goals Correlate types of opportunistic infections related to specific forms of immunodeficiency (cell-mediated, humoral, innate, adaptive, combined) Describe the epidemiology, clinical presentation, diagnosis, treatment approach, and preventative strategies for the opportunistic infections caused by Pneumocystis jirovecii, JC Virus, and Cytomegalovirus Compare and contrast the nature and degree of immunosuppression and the associated opportunistic infections […]