Bone and joint infections
Learning goals Describe the microbiologic agents of bone and joint infections, including age-specific and risk-factor-related pathogens Describe the pathophysiology of osteomyelitis and septic arthritis in terms of risk factors, routes of infection, and anatomic sites Describe the clinical manifestations and diagnostic approach for the different clinical forms of osteomyelitis (acute, chronic, diabetic foot infection) Describe […]
Miscellaneous antibiotics
Learning goals Compare and contrast the mechanism of action and spectrum of activity of the glycopeptides (e.g., vancomycin), the lipopeptides (e.g., daptomycin), and beta-lactams Describe the common clinical uses, adverse effects, and monitoring for vancomycin and daptomycin Describe the mechanism of action, spectrum of activity, common clinical uses, and adverse effects of the fluoroquinolones Describe […]
Spirochetes
Learning goals Describe the distinctive microbiologic and pathogenic features of spirochetes Describe the epidemiology, clinical features, complications, diagnosis, and treatment of leptospirosis Compare and contrast the epidemiology, clinical features, cardinal clinical findings, and treatment for primary, early, and late stage Lyme disease Describe the stages of syphilis including clinical manifestations, interpretation of diagnostic tests, and […]
Atypical skin infections
Learning goals Utilize epidemiology, exposure, and clinical features to create a microbiologic differential diagnosis for lymphocutaneous syndrome Describe the clinical manifestations and diagnosis of leprosy and correlate to the immune response Describe the clinical manifestations and diagnosis of skin conditions due to non-tuberculous mycobacteria Optional study materials These are not required; they are supplementary to […]
Medically relevant anaerobes
Learning goals Summarize the common microbiologic and clinical features of anaerobic infections based on anatomic sites of the disease Compare the epidemiology, pathogenesis, clinical presentation, and toxin mechanism of action for clinical infections caused by Clostridium perfringens Describe the clinical manifestations, diagnosis, and approach to therapy of necrotizing soft tissue infections Compare and contrast the […]
Viral exanthems and common dermatologic manifestations of infectious diseases
Learning goals Compare and contrast the microbiology, clinical manifestations, diagnosis, potential complications, and prevention of common causes of fever and rash in a child: measles, rubella, coxsackie, roseola, scarlet fever, and parvovirus Recall the clinical presentation, potential complications, and treatment of herpes simplex and varicella zoster infections Describe the microbiology and clinical presentation of agents […]
Rickettsia and arthropod-borne viruses
Learning goals Compare and contrast the epidemiology, clinical manifestations, pathogenesis, diagnosis, and treatment of the tick-borne diseases: Rickettsia, Anaplasma, and Ehrlichiosis Compare and contrast the key epidemiologic factors, clinical manifestations, complications, and prevention of dengue fever, chikungunya virus, Zika virus, yellow fever, and arbo-encephalitides Define “vector-borne disease” and “zoonotic disease” and identify strategies to prevent […]
Human immunodeficiency virus (HIV)
Learning goals Describe how the components of the Human Immunodeficiency Virus (HIV) virion, including envelope proteins and enzymes of viral replication, relate to strategies for its diagnosis and treatment Describe the modes of transmission of Human Immunodeficiency Virus (HIV) and the epidemiology (distribution in the population and risk factors, including social determinants) of HIV infection […]
Bioterrorism and other zoonoses
Learning goals Describe the typical clinical presentations of anthrax, tularemia, botulism, plague, and smallpox Describe what makes a microbial agent a good candidate for a bioterrorism weapon and list clues that a bioterrorism incident has occurred in your community Identify the most common zoonotic exposures linked to infections with Bacillus anthracis, Francicella tularensis, Yersinia pestis, […]
Fungal infections
Learning goals Describe the basic structural features of yeasts, molds, and dimorphic fungi and the pathogenesis of fungal infections Compare and contrast the diagnostic methods for various opportunistic fungi, including serologic, histologic, and culture methods Describe the morphology and mycology of Candida and compare and contrast the anatomic sites, clinical manifestations, and approach to management […]