Immune system and rheumatology resources
Systemic sclerosis and Raynaud’s phenomenon
Case study 1: Hae Tap the arrow to view the case.Hae, a 40-year-old woman, is evaluated for a 9-month history of Raynaud phenomenon. She reports no difficulty swallowing, dyspnea on exertion, or hand stiffness. She has recently developed gastroesophageal reflux disease.On physical examination, vital signs are normal. The skin between the distal and proximal interphalangeal […]
Inflammatory myopathies​
Case study 1: Anna MarÃa Tap the arrow to view the case.Anna MarÃa, a 49-year-old woman, presents to her primary care clinic with 5 months of progressive difficulty climbing stairs and lifting objects overhead. She reports needing frequent breaks when folding laundry and brushing her hair.She denies diplopia, ptosis, numbness, tingling, dysphagia, dyspnea, joint swelling, […]
Sjogren’s disease and mixed connective tissue disease​
Case study 1: Suzanne Tap the arrow to view the case.Suzanne, a 44-year-old woman with Sjögren’s disease, presents for routine follow-up. She takes ibuprofen for joint pain and omeprazole for heartburn. She reports no new symptoms.Vital signs are normal. Physical examination reveals tenderness at the proximal interphalangeal and metacarpophalangeal joints bilaterally and bilateral parotid enlargement. The […]
Systemic lupus erythematosus
Case study 1: Blair Tap the arrow to view the case.Blair, a 17-year-old female, presents to the emergency department with progressive shortness of breath for 3 weeks and intermittent hemoptysis for 1 day. She reports painful oral and nasal ulcers, diffuse swelling of her hands and feet, morning stiffness lasting 2 hours, and a 10-pound unintentional […]
Principles of cardiac electrophysiology
If you answered 7 or more of the Pre-Assessment for Principles of Cardiac Electrophysiology questions correctly, you may choose to skip this section. If not, please review this foundational knowledge. An electrical impulse is generated at the sinoatrial (SA) node at regular intervals with a normal frequency of approximately 60 to 100 beats per minute. […]
Pre-assessment for principles of cardiac electrophysiology
To understand the mechanism of action of antiarrhythmic drugs, it is necessary to understand cardiac electrophysiology and the pathophysiology of arrhythmogenesis. Please take the following pre-assessment to gauge your understanding of principles of cardiac electrophysiology as it relates to pharmacology. If you miss two or more questions, you are strongly encouraged to review cardiac electrophysiology and the pathophysiology of arrhythmogenesis from […]
Drugs for dysrhythmias
Learning goals Describe the mechanism of action (including impact on ion channel(s), electrophysiologic action potential, and electrocardiogram) of antiarrhythmic drugs. Identify generic drug names and classify them according to their Singh Vaughan–Williams cardiac antiarrhythmic class. Describe adverse effects and contraindications of antiarrhythmic drugs. Describe drug interactions of antiarrhythmic drugs. Hello and welcome! This module is […]
Critical analysis of a case-control study
This session focuses on the critical analysis of a case-control study. Topics will include: Analysis of a relatively straightforward case-control study addressing a communicable disease outbreak. The application of outbreak investigation principles to a single-source outbreak of Escherichia coli (E. coli) O157:H7 following student field trips. Learning goals Learning activities Required reading Demonstrate respectful, constructive, […]
Critical analysis of a case-control study (Facilitator)
This session focuses on the critical analysis of a case-control study. Topics will include: Analysis of a relatively straightforward case-control study addressing a communicable disease outbreak. The application of outbreak investigation principles to a single-source outbreak of Escherichia coli (E. coli) O157:H7 following student field trips. Learning goals Learning activities Required reading Demonstrate respectful, constructive, […]