Critical appraisal of a prospective cohort study
In this session, we will assess a paper that is a prospective cohort study about community burden and transmission of acute gastroenteritis caused by norovirus and rotavirus. We will also revisit the terms incidence, prevalence, and attack rate. Learning goals Learning activities Required reading Demonstrate respectful, constructive, adaptive interactions with peers and/or facilitators, including punctual […]
Observational study design
Learning Goals Resources Describe the design of case-control studies Discuss biases and confounds in case-control studies Discuss possible ways to deal with confounding in the design or analysis of an observational study Define and discuss the appropriate use of a cross-sectional study Differentiate between real and spurious associations in observational studies Describe a frequent sequence […]
Critical appraisal of a prospective cohort study (Facilitator)
In this session, we will assess a paper that is a prospective cohort study about community burden and transmission of acute gastroenteritis caused by norovirus and rotavirus. We will also revisit the terms incidence, prevalence, and attack rate. Learning goals Learning activities Required reading Demonstrate respectful, constructive, adaptive interactions with peers and/or facilitators, including punctual […]
Differential diagnosis of microangiopathic hemolytic anemia and thrombocytopenia
Feature HUS TTP Scleroderma Renal Crisis (SRC) HELLP Malignant HTN Typical setting Child after diarrheal illness (EHEC) Adults; autoimmune or idiopathic Systemic sclerosis (esp diffuse, early disease) Pregnancy (3rd trimester/postpartum) Long-standing uncontrolled HTN Key trigger Shiga toxin ↓ ADAMTS13 RAAS activation from endothelial injury Placental endothelial dysfunction Severe BP elevation Platelets ↓ ↓↓↓ ↓ ↓ […]
Immune system and rheumatology resources
Systemic sclerosis and Raynaud’s phenomenon
Case study 1: Hae Tap the arrow to view the case.Hae, a 40-year-old woman, is evaluated for a 9-month history of Raynaud phenomenon. She reports no difficulty swallowing, dyspnea on exertion, or hand stiffness. She has recently developed gastroesophageal reflux disease.On physical examination, vital signs are normal. The skin between the distal and proximal interphalangeal […]
Inflammatory myopathies​
Case study 1: Anna MarÃa Tap the arrow to view the case.Anna MarÃa, a 49-year-old woman, presents to her primary care clinic with 5 months of progressive difficulty climbing stairs and lifting objects overhead. She reports needing frequent breaks when folding laundry and brushing her hair.She denies diplopia, ptosis, numbness, tingling, dysphagia, dyspnea, joint swelling, […]
Sjogren’s disease and mixed connective tissue disease​
Case study 1: Suzanne Tap the arrow to view the case.Suzanne, a 44-year-old woman with Sjögren’s disease, presents for routine follow-up. She takes ibuprofen for joint pain and omeprazole for heartburn. She reports no new symptoms.Vital signs are normal. Physical examination reveals tenderness at the proximal interphalangeal and metacarpophalangeal joints bilaterally and bilateral parotid enlargement. The […]
Systemic lupus erythematosus
Case study 1: Blair Tap the arrow to view the case.Blair, a 17-year-old female, presents to the emergency department with progressive shortness of breath for 3 weeks and intermittent hemoptysis for 1 day. She reports painful oral and nasal ulcers, diffuse swelling of her hands and feet, morning stiffness lasting 2 hours, and a 10-pound unintentional […]
Principles of cardiac electrophysiology
If you answered 7 or more of the Pre-Assessment for Principles of Cardiac Electrophysiology questions correctly, you may choose to skip this section. If not, please review this foundational knowledge. An electrical impulse is generated at the sinoatrial (SA) node at regular intervals with a normal frequency of approximately 60 to 100 beats per minute. […]