Differential diagnosis of microangiopathic hemolytic anemia and thrombocytopenia

Feature HUS TTP Scleroderma Renal Crisis (SRC) HELLP Malignant HTN Typical setting Child after diarrheal illness (EHEC) Adults; autoimmune or idiopathic Systemic sclerosis (esp diffuse, early disease) Pregnancy (3rd trimester/postpartum) Long-standing uncontrolled HTN Key trigger Shiga toxin ↓ ADAMTS13 RAAS activation from endothelial injury Placental endothelial dysfunction Severe BP elevation Platelets ↓ ↓↓↓ ↓ ↓ […]

Systemic sclerosis and Raynaud’s phenomenon

Case study 1: Hae Tap the arrow to view the case.Hae, a 40-year-old woman, is evaluated for a 9-month history of Raynaud phenomenon. She reports no difficulty swallowing, dyspnea on exertion, or hand stiffness. She has recently developed gastroesophageal reflux disease.On physical examination, vital signs are normal. The skin between the distal and proximal interphalangeal […]

Miscellaneous rheumatology

Case study 1: Maribell Tap the arrow to view the case.Maribell, a 72-year-old woman, is evaluated for a 3-month history of abdominal and back pain and 4-month history of an increasingly rounded face. On physical examination, vital signs are normal. BMI is 29. Bilateral lacrimal and parotid glands are enlarged. Laboratory evaluation shows a hemoglobin A1c  value […]

Lab 30: Dissection: Posterior Triangle of Neck, Deep Neck, and Root of Neck

Download this lab as a PDF Goals Clean and identify the contents of the posterior triangle of the neck. Perform a deep dissection on one side of the neck to examine the sympathetic trunk and prevertebral muscles. Review the bony anatomy of the superior thoracic aperture and identify its contents. Clean and identify the structures […]