Neurons, Receptors, and Physiologic Ligands/Transmitters
Autonomic System Background To connect GPCRs to the Autonomic Nervous System, it is important to review foundational knowledge. You learned about the Autonomic Nervous System in anatomy. Pharmacology’s focus will be on the receptors of the Autonomic Nervous System and how they elicit various effects in the body. You will learn more details about the […]
GPCR Introduction
G-protein-coupled receptors (GPCRs) G-protein-coupled receptors (GPCRs) are the largest group of membrane receptors. They are cell surface receptors that play a role in an array of functions in the human body. GPCRs play a large role in human physiology and pharmacology. What percentage of medications act by binding GPCRs? 10% INCORRECT Try again 25% INCORRECT […]
Autonomic Nervous System Receptors
What to expect from this module Review of Physiologic Receptors Review of physiologic receptors When we covered Pharmacodynamics, we learned about receptors and drug actions. Recall the basic concept: The therapeutic and toxic effects of drugs result from their interaction with drug targets. Drug targets are often receptors but can also include enzymes, voltage-gated ion […]