Lesson 2. Risk: Basic Principles

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Headshot of Robert (Bob) Lutz, MD, MPH · Public Health course director
Robert (Bob) Lutz
MD, MPH · Public Health course director
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Headshot of Jaime Bowman, MD · Vice Chair, Family Medicine
Jaime Bowman
MD · Vice Chair, Family Medicine
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Headshot of Chaise Zozaya, MPH MBA · Course director
Chaise Zozaya
MPH MBA · Course director
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Table of Contents

Basic principles

Required reading

Clinical Epidemiology: The Essentials, Chapter 5, (P78–91)

  1. Long latency. 
  2. Immediate versus distant causes. 
  3. Common exposure to risk factors. 
  4. Low incidence of disease. 
  5. Small risk. 
  6. Multiple causes and multiple effects. 
  7. Risk factors may or may not be causal. 

Combining multiple factors.

  1. Discrimination. 
  2. Calibration. 
  1. External validation. 
  2. Comparing models. 
  3. Assessing models in clinical practice. 
  1. Risk prediction and pretest probability for diagnostic testing. 
  2. Using risk factors to choose treatment. 
  3. Risk stratification for screening programs. 
  4. Removing risk factors to prevent disease. 

Go to Lesson 2 Knowledge Check

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